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Worldwide dissemination of the blaOXA-23 carbapenemase gene of A. baumannii.
Emerg Infect Dis. 2010 Jan;16(1):35-40
Date: 2010-02-03   Read: 156588

Emerg Infect Dis. 2010 Jan;16(1):35-40

Worldwide dissemination of the blaOXA-23 carbapenemase gene of Acinetobacter baumannii

Mugnier PD, Poirel L, Naas T, Nordmann P

To assess dissemination of OXA-23-producing strains of Acinetobacter baumannii, we obtained 20 carbapenem-resistant, OXA-23-producing isolates from different regions. Their clonal relationship was assessed by pulsed-field gel electrophoresis and multilocus sequence typing. We identified 8 sequence types, including 4 novel types. All except 2 strains belonged to 2 main European clonal lineages. The blaOXA-23 gene was either located on the chromosome or on plasmids and associated with 4 genetic structures.



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