APFID

Home > Latest News on ID > Interesting Papers

LOGIN
Global serotype distribution among S. pneumoniae isolates causing otitis media in children: Potential implications for pneumococcal conjugate vaccines
Date: 2009-06-09   Read: 158721

Vaccine. 2009 Jun 12;27(29):3802-10

Global serotype distribution among Streptococcus pneumoniae isolates causing otitis media in children: Potential implications for pneumococcal conjugate vaccines

Rodgers GL, Arguedas A, Cohen R, Dagan R

Acute otitis media (AOM) is the most common infection following pneumococcal colonization of the upper respiratory tract. Streptococcus pneumoniae causes 30-60% of AOM cases worldwide. However, not all pneumococcal serotypes cause disease and an association exists with nasopharyngeal colonization by certain serotypes and their propensity to cause AOM. This review examines the global serotype distribution relationship between pneumococcal serotypes and AOM in children aged <18 years and demonstrates that the most common pneumococcal serotypes causing AOM globally are 3, 6A, 6B, 9V, 14, 19A, 19F, and 23F.



Next Challenges in the evaluation and licensing of new pneumococcal vaccines, 7-8 July 2008, Ottawa, Canada
Vaccine. 2009 Jun 8;27(28):3681-3688
2009-06-09 157477
Previous Epidemiological evidence for serotype-independent acquired immunity to pneumococcal carriage
J Infect Dis. 2009 Jul 1;200(1):99-106
2009-06-09 160958
޴ٷΰ ΰ