Home > Latest News on ID > Interesting Papers

Antibiotics for community-acquired pneumonia.
J Antimicrob Chemother. 2009;64(6):1123-5.
Date: 2010-02-16   Read: 160394

J Antimicrob Chemother. 2009 Dec;64(6):1123-5.

Antibiotics for community-acquired pneumonia

Dryden M, Hand K, Davey P; BSAC Council

Antibiotic guidelines for community-acquired pneumonia (CAP) often recommend broad-spectrum agents for severe pneumonia. While these may be entirely appropriate in terms of their spectrum of activity and efficacy, there is a risk that such recommendations could result in over-prescribing of broad-spectrum agents with consequent 'collateral damage', meaning superinfection by resistant pathogens, or selection of antibiotic resistance. Narrow-spectrum agents are often as effective and result in less collateral damage. National and local antibiotic guidance should promote choices of agents for narrow-spectrum prescribing even for severe CAP where appropriate.

Next Geographic distribution of S. aureus causing invasive infections in Europe: a molecular-epidemiological analysis. PLoS Med. 2010;7(1):e1000215 2010-03-03 160627
Previous CAP due to pandemic A(H1N1)2009 influenza virus and MRSA co-infection.
PLoS One. 2010;5(1):e8705
2010-02-16 163658
޴ٷΰ ΰ